Product Description:
The Media Filling Machine is an advanced and highly efficient piece of equipment specifically designed for precise and reliable filling of cell culture media. As a state-of-the-art cell culture medium filling machine, it is engineered to meet the stringent requirements of the biotechnology and pharmaceutical industries, ensuring accuracy, hygiene, and consistency in every fill. This cellular culturing media filler excels in handling sensitive biological liquids with utmost care, making it an indispensable tool for laboratories and production facilities involved in cell culturing processes.
One of the standout features of this cell culturing medium filling machine is its comprehensive quality inspection system. The machine is equipped with a sophisticated Filling Volume and Capping Quality Inspection mechanism that thoroughly examines each bottle for unqualified filling volumes, loose caps, and crooked caps. These defects are identified and automatically rejected to maintain the highest quality standards. Additionally, the machine incorporates manual light inspection under LED illumination, with adjustable brightness to detect clarity issues and select unqualified products effectively. This combination of automated and manual inspection ensures that only bottles meeting strict quality criteria proceed to the next stage, minimizing waste and guaranteeing product integrity.
The bottle feeding and separation process is optimized through a bottle feeding screw driven by a precise servo motor. This mechanism ensures smooth and efficient bottle handling by separating bottles accurately before they enter the filling station. The use of a servo motor provides reliable and adjustable control over the bottle feed rate, accommodating different bottle sizes and production speeds. This feature enhances the overall efficiency of the filling line and reduces the risk of bottle jams or misfeeds, which can disrupt production.
The Media Filling Machine operates on a power supply of 380V at 50Hz, with a total power consumption of approximately 11.5KW. This robust power configuration supports the machine’s high-performance components, including the peristaltic pump and servo motors, ensuring stable and continuous operation. The filling room is designed to maintain a controlled environment where the filling process takes place, safeguarding the sterility and quality of the cell culture media.
Compressed air plays a crucial role in the functioning of this cellular culturing media filler, with an operating pressure range of 0.4 to 0.8 Mpa. The compressed air system powers various pneumatic components, contributing to precise bottle handling, capping, and other automated actions. The regulated air pressure ensures consistent performance and helps maintain the machine’s reliability during long production runs.
An integral part of this cell culture medium filling machine is its inline weight checking system. This system performs weighing before filling and utilizes a weighing sensor to control the liquid output of the peristaltic pump accurately. If any bottle exceeds the predetermined weight standard, it is automatically removed from the production line. This feature not only guarantees the correct fill volume but also prevents overfilling, which can lead to product loss and increased costs. The inline weight checking mechanism ensures that each bottle contains the exact amount of cell culture medium required for downstream applications.
In summary, this Media Filling Machine offers a comprehensive solution for the filling of cell culture media, combining precision, reliability, and quality control. Its advanced inspection systems, efficient bottle feeding and separation, robust power requirements, controlled compressed air usage, and inline weight checking make it an ideal cellular culturing media filler for modern biotechnological manufacturing environments. Whether used in small-scale laboratories or large production facilities, this cell culturing medium filling machine delivers exceptional performance, ensuring that cell culture media is accurately filled and securely sealed for optimal cell growth and research outcomes.
Features:
- Product Name: Media Filling Machine
- Machine Material: The material in direct contact with the liquid is 316L stainless steel, or medical polymer materials that meet GMP requirements, such as silicone tubes.
- Capacity:
- 125ml: About 20~24 bottles per minute (subject to actual test)
- 500ml: About 15~17 bottles per minute (subject to actual test)
- Capping Torque: Servo motor control with preset torque on the touch screen (HMI). The servo motor automatically tightens the cap if the torque is not reached, and stops capping once the torque is reached or exceeded.
- Quality Inspection: Includes filling volume and capping quality inspection. Unqualified filling volumes, loose caps, and crooked caps are inspected and rejected. Manual light inspection under adjustable LED illumination is available to detect clarity and select unqualified products.
- Bottle Feeding and Separation: Bottles are separated by a bottle feeding screw driven by a servo motor.
- Suitable for applications as a cell culture media filler, cell culturing media filler, and cell culture medium filling machine.
Technical Parameters:
| Buffer Tank or Buffer Bag |
If a buffer tank is used, it can meet the requirements of high temperature sterilization, equipped with an observation window, a sterile respirator 0.22μm, and a weighing platform with a weighing sensor to control the liquid level. |
| Bottle Specification |
125ml and 500ml square Nalgene aseptic bottles with the same cap. |
| Capping Method |
6 sets of servo motor controlled capping units, each set of capping head servo controlled separately, three-claw capping head. Can reverse loose capping and forward capping for square bottles. |
| Drip-proof Design |
A special liquid receiving tank is designed to prevent liquid drops from dripping after filling with the filling needle. |
| Production Line Composition |
Bottle loading power platform + inner package unpacking platform → Purification buffer zone (liquid supply area) → Decapping → Empty bottle weighing + filling + weighing after filling → Capping → Entering the inspection and rejection area (unqualified weighing, no cap, crooked cap, not tightened inspection, unqualified products enter the dedicated channel, and unqualified products can be specially processed under the laminar flow hood in this area) → Finished products enter the conveyor belt → Automatic film sleeve + heat shrink machine → Collection platform. |
| Capping Torque |
Servo motor control. Preset the capping torque on the touch screen (HMI). If the torque is not reached, the servo motor will automatically tighten the cap. If the torque is reached or exceeded, the servo motor will automatically stop capping. |
| Control Interface |
Each specification product has independent entry buttons and independent operation interfaces, all with mature parameters, convenient for customers to use. |
| Filling Needle Lifting |
Servo motor is used to control the filling needle lifting. The height of bottles of different specifications can be digitally set or adjusted, and the parameters can be stored to prevent splashing and foaming during filling. |
| Quality Inspection |
Filling volume and capping quality inspection. Unqualified filling volume, loose caps, and crooked caps are inspected and rejected. Manual light inspection under LED, etc., with adjustable illumination, to detect clarity and select unqualified products. |
| Glove Box |
Customer optional. The filling host Q2 and Q3 areas can be equipped with 2~3 pairs of glove boxes. |
Applications:
The PERWIN Media Filling Machine, model PW-ZMGX660, is a highly specialized piece of equipment designed for precision and reliability in filling applications, particularly in the pharmaceutical and biotechnology industries. Originating from Qidong, Jiangsu, this machine is certified by internationally recognized standards including CE, ISO, GMP, UL, TUV, and SGS, ensuring it meets the highest quality and safety requirements. Its robust construction and advanced features make it the ideal choice for a variety of filling needs, especially when handling sensitive liquids such as cell culturing mediums.
This cell culturing medium filling machine is widely used in environments where sterility, accuracy, and efficiency are paramount. It is perfect for pharmaceutical manufacturers and biotech companies involved in producing cellular culture mediums, vaccines, and other liquid biological products. The linear positioning filling method combined with weighing filling technology allows for precise calculation of the net liquid weight, ensuring consistent filling volumes. This feature is critical in maintaining the integrity and efficacy of cell culture media and other biologically active substances.
The machine’s filling components are made from 316L stainless steel or medical-grade polymer materials such as silicone tubes, all meeting GMP standards. This ensures that the materials in direct contact with the liquid maintain sterility and prevent contamination, which is essential in sensitive processes like cell culture medium filling. Additionally, the capping system comprises six servo motor-controlled capping units, each independently managed for optimal performance. The three-claw capping heads can handle both forward capping and reverse loose capping specifically for square bottles, enhancing operational flexibility.
In practical scenarios, the PERWIN cellular culture medium filler is used in cleanroom environments where maintaining aseptic conditions is critical. Its quality inspection features include filling volume and capping quality checks, with manual light inspection under adjustable LED illumination to detect clarity and reject unqualified products such as those with loose or crooked caps. The inclusion of a bottle pushing mechanism at the end of the bottle discharging screw guarantees smooth discharge of bottles after filling, preventing mixing with subsequent batches and facilitating sample retention or random inspection of entire groups.
This cell culture medium filling machine is suitable for small to medium-scale production, with a supply ability of 10 units per month and a minimum order quantity of just one unit. The machine is packaged securely in export standard wooden cases and delivered within 60 working days, with payment terms based on TT. Pricing is negotiable to meet the specific needs of clients, making the PERWIN PW-ZMGX660 an excellent investment for businesses seeking reliable, high-quality filling solutions for cell culturing medium and similar liquid products.
Support and Services:
Our Media Filling Machine is designed to provide precise and efficient filling solutions for a variety of media types. To ensure optimal performance and longevity of your equipment, our technical support team is available to assist with installation, operation, and maintenance guidance.
We offer comprehensive services including routine maintenance, troubleshooting, and repair to minimize downtime and keep your production line running smoothly. Our experts can provide on-site support as well as remote assistance to quickly address any issues you may encounter.
For best results, we recommend following the user manual carefully and scheduling regular inspections. Replacement parts and upgrades are also available to enhance the functionality and adapt to evolving production needs.
Our commitment is to deliver reliable and responsive service to support your operations and ensure your Media Filling Machine performs at its best.
FAQ:
Q1: What is the brand and model number of the Media Filling Machine?
A1: The Media Filling Machine is from the brand PERWIN, and the model number is PW-ZMGX660.
Q2: Where is the Media Filling Machine manufactured?
A2: The machine is manufactured in Qidong, Jiangsu, China.
Q3: What certifications does the PERWIN PW-ZMGX660 Media Filling Machine have?
A3: This machine holds multiple certifications including CE, ISO, GMP, UL, TUV, and SGS.
Q4: What is the minimum order quantity and the price for the Media Filling Machine?
A4: The minimum order quantity is 1 unit, and the price is negotiable based on order details.
Q5: What are the packaging details and delivery time for the machine?
A5: The machine is packaged in export standard wooden cases, and the delivery time is approximately 60 working days.
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